ATG7 Rabbit rabbit pAb
ENT-A16048
Description
| REF | ENT-A16048 |
|---|---|
| Category | Antibody Polyclonal |
| Description | ATG7 Rabbit rabbit pAb |
| Source | Rabbit |
| Applications | WB;IHC;IF |
| Reactivity | Human;Mouse;Rat |
| Reactivity | Human;Mouse;Rat |
| Dilution | IHC-p 1:50-300,WB 1:500-2000 |
| Immunogen | Recombinant Protein of ATG7 |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | 78kD |
| Human Gene ID | 10533 |
| Human Swiss Prot Nº | O95352 |
| Subcellular Location | Cytoplasm . Preautophagosomal structure . Localizes also to discrete punctae along the ciliary axoneme and to the base of the ciliary axoneme. . |
Other Name: Ubiquitin-like modifier-activating enzyme ATG7 (ATG12-activating enzyme E1 ATG7;Autophagy-related protein 7;APG7-like;hAGP7;Ubiquitin-activating enzyme E1-like protein)
Background: This gene encodes an E1-like activating enzyme that is essential for autophagy and cytoplasmic to vacuole transport. The encoded protein is also thought to modulate p53-dependent cell cycle pathways during prolonged metabolic stress. It has been associated with multiple functions, including axon membrane trafficking, axonal homeostasis, mitophagy, adipose differentiation, and hematopoietic stem cell maintenance. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015],