ATG5 Rabbit pAb
ENT-A1370
Description
| REF | ENT-A1370 |
|---|---|
| Category | Antibody Polyclonal |
| Description | ATG5 Rabbit pAb |
| Source | Rabbit |
| Applications | IHC |
| Reactivity | Human, Mouse, Rat |
| Reactivity | Human, Mouse, Rat |
| Dilution | IHC 1:100-200 |
| Immunogen | Recombinant Protein |
| Storage Stability | PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles. |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1mg/mL |
| Observed Band KD | 32kDa |
| Human Gene ID | 9494 |
| Human Swiss Prot Nº | Q9H1Y0 |
| Subcellular Location | Cytoplasm, Membrane |
Other Name: APG5, APG5L,ASP,Autophage Cysteine protein5 antibody
Background: Autophagy is generally activated by conditions of nutrient deprivation but has also been associated with a number of physiological processes including development, differentiation, neurodegeneration, infection, and cancer. Formation of the autophagosome involves a ubiquitin-like conjugation system in which Atg12 is covalently bound to Atg5 and targeted to autophagosome vesicles. This conjugation reaction is mediated by the ubiquitin E1-like enzyme Atg7 and the E2-like enzyme Atg10.