ATG5 (3C7) Mouse mAb
ENT-A1620
Description
| Ref | ENT-A1620 |
|---|---|
| Category | Antibody Monoclonal |
| Alternative Name | APG5, APG5L, ASP, Autophagy protein 5 antibody |
| Application | WB, IHC |
| Source | Mouse |
| Reactivity | Human, Mouse, Rat |
| Dilution | WB 1:5,000-10,000 IHC 1:100-200 |
| Immunogen | Recombinant Protein |
| Storage Stability | PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles. |
| Clonality | Monoclonal |
| Isotype | IgG1 |
| Concentration | 1mg/mL |
| Observed Band(KD) | 55kDa |
| Human Gene ID | 9494 |
| Human Swiss Prot No | Q9H1Y0 |
| Subcellular Location | Cytoplasm, Membrane |
Background: Autophagy is generally activated by conditions of nutrient deprivation but has also been associated with a number of physiological processes including development, differentiation, neurodegeneration, infection, and cancer. Formation of the autophagosome involves a ubiquitin-like conjugation system in which Atg12 is covalently bound to Atg5 and targeted to autophagosome vesicles. This conjugation reaction is mediated by the ubiquitin E1-like enzyme Atg7 and the E2-like enzyme Atg10.