ASPP1 rabbit pAb
ENT-A8129
Description
| REF | ENT-A8129 |
|---|---|
| Category | Antibody Polyclonal |
| Description | ASPP1 rabbit pAb |
| Source | Rabbit |
| Applications | IHC;IF;ELISA |
| Reactivity | Human;Rat;Mouse; |
| Reactivity | Human;Rat;Mouse; |
| Dilution | IHC-p 1:50-200, ELISA 1:10000-20000 |
| Immunogen | Synthetic peptide from human protein at AA range: 630-680 |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | |
| Human Gene ID | 23368 |
| Human Swiss Prot Nº | Q96KQ4 |
| Subcellular Location | Cytoplasm . Nucleus . Predominantly cytoplasmic. Some fraction is nuclear. |
Other Name: Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B)
Background: This gene encodes a member of the ASPP (apoptosis-stimulating protein of p53) family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. ASPP proteins are required for the induction of apoptosis by p53-family proteins. They promote DNA binding and transactivation of p53-family proteins on the promoters of proapoptotic genes. Expression of this gene is regulated by the E2F transcription factor. [provided by RefSeq, Jul 2008],