ARHG6 rabbit pAb
ENT-A9462
Description
| REF | ENT-A9462 |
|---|---|
| Category | Antibody Polyclonal |
| Description | ARHG6 rabbit pAb |
| Source | Rabbit |
| Applications | WB;ELISA |
| Reactivity | Human;Rat;Mouse |
| Reactivity | Human;Rat;Mouse |
| Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Immunogen | Synthesized peptide derived from human protein . at AA range: 580-660 |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | 85kD |
| Human Gene ID | 9459 |
| Human Swiss Prot Nº | Q15052 |
| Subcellular Location | Cell projection, lamellipodium . |
Other Name:
Background: Rac/Cdc42 guanine nucleotide exchange factor 6(ARHGEF6) Homo sapiens Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein belongs to a family of cytoplasmic proteins that activate the Ras-like family of Rho proteins by exchanging bound GDP for GTP. It may form a complex with G proteins and stimulate Rho-dependent signals. This protein is activated by PI3-kinase. Mutations in this gene can cause X-chromosomal non-specific mental retardation. [provided by RefSeq, Jul 2008],