AMPKα1/2 rabbit pAb
ENT-A2142
Description
| REF | ENT-A2142 |
|---|---|
| Category | Antibody Polyclonal |
| Description | AMPKα1/2 rabbit pAb |
| Source | Rabbit |
| Applications | WB;IHC;IF;ELISA |
| Reactivity | Human;Mouse;Rat;Monkey;Bovine |
| Reactivity | Human;Mouse;Rat;Monkey;Bovine |
| Dilution | WB 1:500-2000;IHC-p 1:100-500;IF/ICC 1:100-500;ELISA 1:5000-20000 |
| Immunogen | The antiserum was produced against synthesized peptide derived from human AMPK alpha. AA range:140-189 |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | 63kD |
| Human Gene ID | 5562/5563 |
| Human Swiss Prot Nº | Q13131/P54646 |
| Subcellular Location | Cytoplasm . Nucleus . In response to stress, recruited by p53/TP53 to specific promoters. . |
Other Name: PRKAA1; AMPK1; 5′-AMP-activated protein kinase catalytic subunit alpha-1; AMPK subunit alpha-1; Acetyl-CoA carboxylase kinase; ACACA kinase; Hydroxymethylglutaryl-CoA reductase kinase; HMGCR kinase; Tau-protein kinase PRKAA1; PRKAA2; AMPK;
Background: The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5′-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008],