ALS rabbit pAb
ENT-A5800
Description
| REF | ENT-A5800 |
|---|---|
| Category | Antibody Polyclonal |
| Description | ALS rabbit pAb |
| Source | Rabbit |
| Applications | WB;ELISA |
| Reactivity | Human;Rat;Mouse; |
| Reactivity | Human;Rat;Mouse; |
| Dilution | Western Blot: 1/500 – 1/2000. ELISA: 1/10000. Not yet tested in other applications. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human IGFALS. AA range:303-352 |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | 66kD |
| Human Gene ID | 3483 |
| Human Swiss Prot Nº | P35858 |
| Subcellular Location | Secreted, extracellular space. |
Other Name: IGFALS; ALS; Insulin-like growth factor-binding protein complex acid labile subunit; ALS
Background: The protein encoded by this gene is a serum protein that binds insulin-like growth factors, increasing their half-life and their vascular localization. Production of the encoded protein, which contains twenty leucine-rich repeats, is stimulated by growth hormone. Defects in this gene are a cause of acid-labile subunit deficiency, which maifests itself in a delayed and slow puberty. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Mar 2009],