AHR rabbit pAb
ENT-A14314
Description
| REF | ENT-A14314 |
|---|---|
| Category | Antibody Polyclonal |
| Description | AHR rabbit pAb |
| Source | Rabbit |
| Applications | WB; IF |
| Reactivity | Human; Mouse;Rat;Fish |
| Reactivity | Human; Mouse;Rat;Fish |
| Dilution | WB 1:500-2000; IF/ICC 1:100-500 |
| Immunogen | Synthesized peptide derived from human AHR AA range: 408-458 |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | |
| Human Gene ID | 196 |
| Human Swiss Prot Nº | P35869 |
| Subcellular Location | Cytoplasm . Nucleus . Initially cytoplasmic; upon binding with ligand and interaction with a HSP90, it translocates to the nucleus. . |
Other Name:
Background: The protein encoded by this gene is a ligand-activated helix-loop-helix transcription factor involved in the regulation of biological responses to planar aromatic hydrocarbons. This receptor has been shown to regulate xenobiotic-metabolizing enzymes such as cytochrome P450. Before ligand binding, the encoded protein is sequestered in the cytoplasm; upon ligand binding, this protein moves to the nucleus and stimulates transcription of target genes. [provided by RefSeq, Sep 2015],