AFF4 rabbit pAb
ENT-A8663
Description
| REF | ENT-A8663 |
|---|---|
| Category | Antibody Polyclonal |
| Description | AFF4 rabbit pAb |
| Source | Rabbit |
| Applications | WB;ELISA |
| Reactivity | Human;Mouse |
| Reactivity | Human;Mouse |
| Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Immunogen | Synthesized peptide derived from human protein . at AA range: 30-110 |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | 127kD |
| Human Gene ID | 27125 |
| Human Swiss Prot Nº | Q9UHB7 |
| Subcellular Location | Nucleus . Associates to transcriptionally active chromatin but not at snRNA genes. . |
Other Name:
Background: The protein encoded by this gene belongs to the AF4 family of transcription factors involved in leukemia. It is a component of the positive transcription elongation factor b (P-TEFb) complex. A chromosomal translocation involving this gene and MLL gene on chromosome 11 is found in infant acute lymphoblastic leukemia with ins(5;11)(q31;q31q23). [provided by RefSeq, Oct 2011],