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ADCY5 rabbit pAb

ADCY5 rabbit pAb

ENT-A14331

Description

 

 

 

REF ENT-A14331
Category Antibody Polyclonal
Description ADCY5 rabbit pAb
Source Rabbit
Applications WB
Reactivity Human; Mouse;Rat
Reactivity Human; Mouse;Rat
Dilution WB 1:500-2000
Immunogen Synthesized peptide derived from human ADCY5 AA range: 471-521
Storage Stability -20°C/1 year
Clonality Polyclonal
Isotype IgG
Concentration 1 mg/ml
Observed Band KD
Human Gene ID 111
Human Swiss Prot Nº O95622
Subcellular Location Cell membrane ; Multi-pass membrane protein. Cell projection, cilium .

Other Name:

Background: This gene encodes a member of the membrane-bound adenylyl cyclase enzymes. Adenylyl cyclases mediate G protein-coupled receptor signaling through the synthesis of the second messenger cAMP. Activity of the encoded protein is stimulated by the Gs alpha subunit of G protein-coupled receptors and is inhibited by protein kinase A, calcium and Gi alpha subunits. Single nucleotide polymorphisms in this gene may be associated with low birth weight and type 2 diabetes. Alternatively spliced transcript variants that encode different isoforms have been observed for this gene. [provided by RefSeq, Dec 2010],