Active Caspase 3 Mouse mAb
ENT-A1538
Description
| Ref | ENT-A1538 |
|---|---|
| Category | Antibody Monoclonal |
| Alternative Name | APOPAIN antibody, CASP 3 antibody, CPP32 antibody, Cysterine protease CPP32 antibody |
| Application | WB, IHC |
| Source | Mouse |
| Reactivity | Human, Rat, Mouse |
| Dilution | WB 1:500-1,000 IHC 1:100-200 |
| Immunogen | Recombinant Protein |
| Storage Stability | PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles. |
| Clonality | Monoclonal |
| Isotype | IgG1 |
| Concentration | 1mg/mL |
| Observed Band(KD) | 17kDa |
| Human Gene ID | 836 |
| Human Swiss Prot No | P42574 |
| Subcellular Location | Cytoplasm |
Background: Activation of caspase-3 requires proteolytic processing of its inactive zymogen into activated p17 and p12 fragments. Cleavage of caspase-3 requires aspartic acid at the P1 position.