Acetyl P53(K382) (1G7) Mouse mAb
ENT-A1622
Description
| Ref | ENT-A1622 |
|---|---|
| Category | Antibody Monoclonal |
| Alternative Name | Cellular tumor antigen p53 antibody, Cys 51 stop antibody, Tp53 antibody, Tumor protein p53 antibody |
| Application | IHC |
| Source | Mouse |
| Reactivity | Human, Mouse, Rat |
| Dilution | IHC 1:100-200 |
| Immunogen | Synthetic Peptide |
| Storage Stability | PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles. |
| Clonality | Monoclonal |
| Isotype | IgG1 |
| Concentration | 1mg/mL |
| Observed Band(KD) | 53kDa |
| Human Gene ID | 7157 |
| Human Swiss Prot No | P04637 |
| Subcellular Location | Cytoplasm,Cytoplasm. Nucleus |
Background: p53 plays a major role in the cellular response to DNA damage and other genomic aberrations. The activation of p53 can lead to either cell cycle arrest and DNA repair, or apoptosis. Acetylation appears to play a positive role in the accumulation of p53 protein in stress response.