14-3-3 ζ (phospho Ser58) rabbit pAb
ENT-A2009
Description
| REF | ENT-A2009 |
|---|---|
| Category | Antibody Polyclonal |
| Description | 14-3-3 ζ (phospho Ser58) rabbit pAb |
| Source | Rabbit |
| Applications | WB;IHC;IF;ELISA |
| Reactivity | Human;Mouse;Rat |
| Reactivity | Human;Mouse;Rat |
| Dilution | Western Blot: 1/500 – 1/2000. Immunohistochemistry: 1/100 – 1/300. Immunofluorescence: 1/200 – 1/1000. ELISA: 1/40000. Not yet tested in other applications. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human 14-3-3 zeta around the phosphorylation site of Ser58. AA range:24-73 |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | 30kD |
| Human Gene ID | 7534 |
| Human Swiss Prot Nº | P63104 |
| Subcellular Location | Cytoplasm . Melanosome . Located to stage I to stage IV melanosomes. |
Other Name: YWHAZ; 14-3-3 protein zeta/delta; Protein kinase C inhibitor protein 1; KCIP-1
Background: This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and sheep orthologs. The encoded protein interacts with IRS1 protein, suggesting a role in regulating insulin sensitivity. Several transcript variants that differ in the 5′ UTR but that encode the same protein have been identified for this gene. [provided by RefSeq, Oct 2008],