Recombinant Human MetAP1D (N, C-6His)
Recombinant Human Methionine AminopESCItidase 1D Mitochondrial is produced by our E.coli expression system and the target gene encoding Arg44-Ala335 is expressed with a 6His tag at the N-terminus, 6His tag at the C-terminus.
Description
| Reference | ESCIT270 |
|---|---|
| Size | 50ug |
| Molecular Weight | 35.4 KDa |
| Purity | Greater than 95% as determined by reducing SDS-PAGE. |
| Endotoxin | Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
| Biological Activity |
Other names: Methionine AminopESCItidase 1D Mitochondrial; Methionyl AminopESCItidase Type 1D Mitochondrial; METAP1D; MAP1D
Redissolve:
Storage: Store at ?-70°C, stable for 6 months after receipt.
Store at ?-70°C, stable for 3 months under sterile conditions after opening.
Please minimize freeze-thaw cycles.
Background: Methionine AminopESCItidase 1D (METAP1D) is a mitochondrion protein that belongs to the pESCItidase M24A family. METAP1D is overexpressed at the protein level in colon cancer cell lines and colon tumors as compared to normal tissues. N-terminal methionine removal is an important cellular process required for proper biological activity, subcellular localization, and eventual degradation of many proteins. METAP1D is also active with zinc, manganese or divalent ions. It may also play an important role in colon tumorigenesis.