KCNK9 (TASK-3) rabbit pAb
ENT-A15985
Description
| REF | ENT-A15985 |
|---|---|
| Category | Antibody Polyclonal |
| Description | KCNK9 (TASK-3) rabbit pAb |
| Source | Rabbit |
| Applications | WB;IHC;IF |
| Reactivity | Human;Rat;Mouse |
| Reactivity | Human;Rat;Mouse |
| Dilution | WB 1:1000-2000, IHC 1:100-200 |
| Immunogen | Synthetic Peptide of KCNK9 (TASK-3) AA range: 220-270 |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | 42kD |
| Human Gene ID | 51305 |
| Human Swiss Prot Nº | Q9NPC2 |
| Subcellular Location | Cell membrane ; Multi-pass membrane protein . |
Other Name: Potassium channel subfamily K member 9 (Acid-sensitive potassium channel protein TASK-3;TWIK-related acid-sensitive K(+) channel 3;Two pore potassium channel KT3.2;Two pore K(+) channel KT3.2)
Background: This gene encodes a protein that contains multiple transmembrane regions and two pore-forming P domains and functions as a pH-dependent potassium channel. Amplification and overexpression of this gene have been observed in several types of human carcinomas. This gene is imprinted in the brain, with preferential expression from the maternal allele. A mutation in this gene was associated with Birk-Barel mental retardation dysmorphism syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013],