PROC (light chain, Cleaved-Leu179) rabbit pAb
ENT-A15574
Description
| REF | ENT-A15574 |
|---|---|
| Category | Antibody Polyclonal |
| Description | PROC (light chain, Cleaved-Leu179) rabbit pAb |
| Source | Rabbit |
| Applications | WB;ELISA;IHC |
| Reactivity | Human;Rat;Mouse; |
| Reactivity | Human;Rat;Mouse; |
| Dilution | WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000 |
| Immunogen | Synthesized peptide derived from human PROC (light chain, Cleaved-Leu179) |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | 17 45kD |
| Human Gene ID | 5624 |
| Human Swiss Prot Nº | P04070 |
| Subcellular Location | Secreted . Golgi apparatus . Endoplasmic reticulum . |
Other Name: Vitamin K-dependent protein C (EC 3.4.21.69;Anticoagulant protein C;Autoprothrombin IIA;Blood coagulation factor XIV) [Cleaved into: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide]
Background: This gene encodes a vitamin K-dependent plasma glycoprotein. The encoded protein is cleaved to its activated form by the thrombin-thrombomodulin complex. This activated form contains a serine protease domain and functions in degradation of the activated forms of coagulation factors V and VIII. Mutations in this gene have been associated with thrombophilia due to protein C deficiency, neonatal purpura fulminans, and recurrent venous thrombosis.[provided by RefSeq, Dec 2009],