EMR2 (Cleaved-Leu517) rabbit pAb
ENT-A15518
Description
| REF | ENT-A15518 |
|---|---|
| Category | Antibody Polyclonal |
| Description | EMR2 (Cleaved-Leu517) rabbit pAb |
| Source | Rabbit |
| Applications | WB; ELISA |
| Reactivity | Human |
| Reactivity | Human |
| Dilution | WB 1:1000-2000 ELISA 1:5000-20000 |
| Immunogen | Synthesized peptide derived from human EMR2 (Cleaved-Leu517) |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | 57kD |
| Human Gene ID | 30817 |
| Human Swiss Prot Nº | Q9UHX3 |
| Subcellular Location | Cell membrane ; Multi-pass membrane protein. Cell projection, ruffle membrane ; Multi-pass membrane protein. Localized at the leading edge of migrating cells. . |
Other Name: EGF-like module-containing mucin-like hormone receptor-like 2 (EGF-like module receptor 2;CD antigen CD312)
Background: This gene encodes a member of the class B seven-span transmembrane (TM7) subfamily of G-protein coupled receptors. These proteins are characterized by an extended extracellular region with a variable number of N-terminal epidermal growth factor-like domains coupled to a TM7 domain via a mucin-like spacer domain. The encoded protein is expressed mainly in myeloid cells where it promotes cell-cell adhesion through interaction with chondroitin sulfate chains. This gene is situated in a cluster of related genes on chromosome 19. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2012],