DFF45 (Cleaved-Thr225) rabbit pAb
ENT-A15515
Description
| REF | ENT-A15515 |
|---|---|
| Category | Antibody Polyclonal |
| Description | DFF45 (Cleaved-Thr225) rabbit pAb |
| Source | Rabbit |
| Applications | WB; ELISA |
| Reactivity | Human;Rat;Mouse; |
| Reactivity | Human;Rat;Mouse; |
| Dilution | WB 1:1000-2000 ELISA 1:5000-20000 |
| Immunogen | Synthesized peptide derived from human DFF45 (Cleaved-Thr225) |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | 12 36kD |
| Human Gene ID | 1676 |
| Human Swiss Prot Nº | O00273 |
| Subcellular Location | Cytoplasm. |
Other Name: DNA fragmentation factor subunit alpha (DNA fragmentation factor 45 kDa subunit;DFF-45;Inhibitor of CAD;ICAD)
Background: function:Inhibitor of the caspase-activated DNase (DFF40).,PTM:Caspase-3 cleaves DFF45 at 2 sites to generate an active factor.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 CIDE-N domain.,subunit:Heterodimer of DFFA and DFFB.,