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BEX2 rabbit pAb

BEX2 rabbit pAb

ENT-A14143

Description

 

 

 

REF ENT-A14143
Category Antibody Polyclonal
Description BEX2 rabbit pAb
Source Rabbit
Applications WB
Reactivity Human; Mouse;Rat
Reactivity Human; Mouse;Rat
Dilution WB 1:500-2000
Immunogen Synthesized peptide derived from human BEX2 AA range: 28-78
Storage Stability -20°C/1 year
Clonality Polyclonal
Isotype IgG
Concentration 1 mg/ml
Observed Band KD
Human Gene ID 84707
Human Swiss Prot Nº Q9BXY8
Subcellular Location Cytoplasm . Nucleus .

Other Name:

Background: This gene belongs to the brain expressed X-linked gene family. The encoded protein interacts with the transcription factor LIM domain only 2 in a DNA-binding complex that recognizes the E-box element and promotes transcription. This gene has been found to be a tumor suppressor that is silenced in human glioma. In breast cancer cells, this gene product modulates apoptosis in response to estrogen and tamoxifen, and enhances the anti-proliferative effect of tamoxifen. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009],