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CNIH2 rabbit pAb

CNIH2 rabbit pAb

ENT-A13839

Description

 

 

 

REF ENT-A13839
Category Antibody Polyclonal
Description CNIH2 rabbit pAb
Source Rabbit
Applications WB
Reactivity Human; Mouse;Rat
Reactivity Human; Mouse;Rat
Dilution WB 1:500-2000
Immunogen Synthesized peptide derived from human CNIH2 AA range: 10-60
Storage Stability -20°C/1 year
Clonality Polyclonal
Isotype IgG
Concentration 1 mg/ml
Observed Band KD
Human Gene ID 254263
Human Swiss Prot Nº Q6PI25
Subcellular Location Endoplasmic reticulum membrane ; Multi-pass membrane protein . Cell junction, synapse, postsynaptic cell membrane ; Multi-pass membrane protein . Cell projection, dendrite . Cell projection, dendritic spine . Cell junction, synapse, postsynaptic density . Also localizes to the cell membrane of extrasynaptic sites (dendritic shafts, spines of pyramidal cells). .

Other Name:

Background: The protein encoded by this gene is an auxiliary subunit of the ionotropic glutamate receptor of the AMPA subtype. AMPA receptors mediate fast synaptic neurotransmission in the central nervous system. This protein has been reported to interact with the Type I AMPA receptor regulatory protein isoform gamma-8 to control assembly of hippocampal AMPA receptor complexes, thereby modulating receptor gating and pharmacology. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012],