CPT1A rabbit pAb
ENT-A13792
Description
| REF | ENT-A13792 |
|---|---|
| Category | Antibody Polyclonal |
| Description | CPT1A rabbit pAb |
| Source | Rabbit |
| Applications | WB |
| Reactivity | Human; Mouse;Rat;Canine |
| Reactivity | Human; Mouse;Rat;Canine |
| Dilution | WB 1:500-2000 |
| Immunogen | Synthesized peptide derived from human CPT1A. AA range 40-80 |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | 85kD |
| Human Gene ID | 1374 |
| Human Swiss Prot Nº | P50416 |
| Subcellular Location | Mitochondrion outer membrane ; Multi-pass membrane protein . |
Other Name: Carnitine O-palmitoyltransferase 1, liver isoform (CPT1-L) (EC 2.3.1.21) (Carnitine O-palmitoyltransferase I, liver isoform) (CPT I) (CPTI-L) (Carnitine palmitoyltransferase 1A)
Background: The mitochondrial oxidation of long-chain fatty acids is initiated by the sequential action of carnitine palmitoyltransferase I (which is located in the outer membrane and is detergent-labile) and carnitine palmitoyltransferase II (which is located in the inner membrane and is detergent-stable), together with a carnitine-acylcarnitine translocase. CPT I is the key enzyme in the carnitine-dependent transport across the mitochondrial inner membrane and its deficiency results in a decreased rate of fatty acid beta-oxidation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],