DARPP-32 (phospho-Ser97) rabbit pAb
ENT-A13703
Description
| REF | ENT-A13703 |
|---|---|
| Category | Antibody Polyclonal |
| Description | DARPP-32 (phospho-Ser97) rabbit pAb |
| Source | Rabbit |
| Applications | WB |
| Reactivity | Human;Mouse;Rat |
| Reactivity | Human;Mouse;Rat |
| Dilution | WB 1:1000-2000 |
| Immunogen | Synthesized phosho peptide around human DARPP-32 (Ser97) |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | 30kD |
| Human Gene ID | 84152 |
| Human Swiss Prot Nº | Q9UD71 |
| Subcellular Location | Cytoplasm. |
Other Name: Protein phosphatase 1 regulatory subunit 1B (DARPP-32) (Dopamine- and cAMP-regulated neuronal phosphoprotein)
Background: This gene encodes a bifunctional signal transduction molecule. Dopaminergic and glutamatergic receptor stimulation regulates its phosphorylation and function as a kinase or phosphatase inhibitor. As a target for dopamine, this gene may serve as a therapeutic target for neurologic and psychiatric disorders. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011],