DISC1 rabbit pAb
ENT-A13639
Description
| REF | ENT-A13639 |
|---|---|
| Category | Antibody Polyclonal |
| Description | DISC1 rabbit pAb |
| Source | Rabbit |
| Applications | WB |
| Reactivity | Human; Mouse;Rat |
| Reactivity | Human; Mouse;Rat |
| Dilution | WB 1：500-2000 |
| Immunogen | Synthesized peptide derived from human DISC1 AA range: 423-473 |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | |
| Human Gene ID | 27185 |
| Human Swiss Prot Nº | Q9NRI5 |
| Subcellular Location | Cytoplasm . Cytoplasm, cytoskeleton . Mitochondrion . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cell junction, synapse, postsynaptic density . Colocalizes with NDEL1 in the perinuclear region and the centrosome (By similarity). Localizes to punctate cytoplasmic foci which overlap in part with mitochondria (PubMed:12506198, PubMed:15797709). Colocalizes with PCNT at the centrosome (PubMed:18955030). . |
Other Name:
Background: This gene encodes a protein with multiple coiled coil motifs which is located in the nucleus, cytoplasm and mitochondria. The protein is involved in neurite outgrowth and cortical development through its interaction with other proteins. This gene is disrupted in a t(1;11)(q42.1;q14.3) translocation which segregates with schizophrenia and related psychiatric disorders in a large Scottish family. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008],