EI24 rabbit pAb
ENT-A13548
Description
| REF | ENT-A13548 |
|---|---|
| Category | Antibody Polyclonal |
| Description | EI24 rabbit pAb |
| Source | Rabbit |
| Applications | WB |
| Reactivity | Human; Mouse;Rat |
| Reactivity | Human; Mouse;Rat |
| Dilution | WB 1：500-2000 |
| Immunogen | Synthesized peptide derived from human EI24 AA range: 107-157 |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | |
| Human Gene ID | 9538 |
| Human Swiss Prot Nº | O14681 |
| Subcellular Location | Nucleus membrane ; Multi-pass membrane protein . Cytoplasm . Endoplasmic reticulum membrane ; Multi-pass membrane protein . |
Other Name:
Background: This gene encodes a putative tumor suppressor and has higher expression in p53-expressing cells than in control cells and is an immediate-early induction target of p53-mediated apoptosis. The encoded protein may suppress cell growth by inducing apoptotic cell death through the caspase 9 and mitochondrial pathways. This gene is located on human chromosome 11q24, a region frequently altered in cancers. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene have been defined on chromosomes 1, 3, 7, and 8. [provided by RefSeq, Feb 2014],