FKBP1B Rabbit pAb
ENT-A13342
Description
| REF | ENT-A13342 |
|---|---|
| Category | Antibody Polyclonal |
| Description | FKBP1B Rabbit pAb |
| Source | Rabbit |
| Applications | IHC; ELISA |
| Reactivity | Human;Rat;Mouse; |
| Reactivity | Human;Rat;Mouse; |
| Dilution | IHC-p 1:50-200, ELISA(peptide)1:5000-20000 |
| Immunogen | Synthesized peptide derived from human FKBP1B AA range: 35-85 |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | |
| Human Gene ID | 2281 |
| Human Swiss Prot Nº | P68106 |
| Subcellular Location | Cytoplasm . Sarcoplasmic reticulum . |
Other Name: Peptidyl-prolyl cis-trans isomerase FKBP1B (PPIase FKBP1B;EC 5.2.1.8;12.6 kDa FK506-binding protein;12.6 kDa FKBP;FKBP-12.6;FK506-binding protein 1B;FKBP-1B;Immunophilin FKBP12.6;Rotamase;h-FKBP-12)
Background: The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It is highly similar to the FK506-binding protein 1A. Its physiological role is thought to be in excitation-contraction coupling in cardiac muscle. There are two alternatively spliced transcript variants of this gene encoding different isoforms. [provided by RefSeq, Jul 2008],