HEM1 rabbit pAb
ENT-A13146
Description
| REF | ENT-A13146 |
|---|---|
| Category | Antibody Polyclonal |
| Description | HEM1 rabbit pAb |
| Source | Rabbit |
| Applications | WB |
| Reactivity | Human; Mouse;Rat |
| Reactivity | Human; Mouse;Rat |
| Dilution | WB 1：500-2000 |
| Immunogen | Synthesized peptide derived from human HEM1 AA range: 87-137 |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | |
| Human Gene ID | 211 |
| Human Swiss Prot Nº | P13196 |
| Subcellular Location | Mitochondrion inner membrane ; Peripheral membrane protein . Localizes to the matrix side of the mitochondrion inner membrane. . |
Other Name:
Background: This gene encodes the mitochondrial enzyme which is catalyzes the rate-limiting step in heme (iron-protoporphyrin) biosynthesis. The enzyme encoded by this gene is the housekeeping enzyme; a separate gene encodes a form of the enzyme that is specific for erythroid tissue. The level of the mature encoded protein is regulated by heme: high levels of heme down-regulate the mature enzyme in mitochondria while low heme levels up-regulate. A pseudogene of this gene is located on chromosome 12. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2015],