HSH2D rabbit pAb
ENT-A13112
Description
| REF | ENT-A13112 |
|---|---|
| Category | Antibody Polyclonal |
| Description | HSH2D rabbit pAb |
| Source | Rabbit |
| Applications | WB |
| Reactivity | Human; Mouse |
| Reactivity | Human; Mouse |
| Dilution | WB 1:500-2000 |
| Immunogen | Synthesized peptide derived from human HSH2D AA range: 288-338 |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | 38kD |
| Human Gene ID | 84941 |
| Human Swiss Prot Nº | Q96JZ2 |
| Subcellular Location | Cytoplasm. Nucleus. |
Other Name: Hematopoietic SH2 domain-containing protein (Hematopoietic SH2 protein) (Adaptor in lymphocytes of unknown function X)
Background: T-cell activation requires 2 signals: recognition of antigen by the T-cell receptor (see TCR; MIM 186880) and a costimulatory signal provided primarily by CD28 (MIM 186760) in naive T cells. HSH2 is a target of both of these signaling pathways (Greene et al., 2003 [PubMed 12960172]).[supplied by OMIM, Mar 2008],