LCTL rabbit pAb
ENT-A12887
Description
| REF | ENT-A12887 |
|---|---|
| Category | Antibody Polyclonal |
| Description | LCTL rabbit pAb |
| Source | Rabbit |
| Applications | WB |
| Reactivity | Human; Mouse |
| Reactivity | Human; Mouse |
| Dilution | WB 1:500-2000 |
| Immunogen | Synthesized peptide derived from human LCTL AA range: 450-500 |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | 60kD |
| Human Gene ID | 197021 |
| Human Swiss Prot Nº | Q6UWM7 |
| Subcellular Location | Endoplasmic reticulum membrane ; Single-pass membrane protein . |
Other Name: Lactase-like protein (Klotho/lactase-phlorizin hydrolase-related protein)
Background: This gene encodes a member of family 1 glycosidases. Glycosidases are enzymes that hydrolyze glycosidic bonds and are classified into families based on primary amino acid sequence. Most members of family 1 have two conserved glutamic acid residues, which are required for enzymatic activity. The mouse ortholog of this protein has been characterized and has a domain structure of an N-terminal signal peptide, glycosidase domain, transmembrane domain, and a short cytoplasmic tail. It lacks one of the conserved glutamic acid residues important for catalysis, and its function remains to be determined (PMID: 12084582). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013],