MARCKS (phospho-Ser167/170) rabbit pAb
ENT-A12787
Description
| REF | ENT-A12787 |
|---|---|
| Category | Antibody Polyclonal |
| Description | MARCKS (phospho-Ser167/170) rabbit pAb |
| Source | Rabbit |
| Applications | WB |
| Reactivity | Human;Mouse;Rat |
| Reactivity | Human;Mouse;Rat |
| Dilution | WB 1:1000-2000 |
| Immunogen | Synthesized phosho peptide around human MARCKS (Ser167 and 170) |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | 32kD |
| Human Gene ID | 4082 |
| Human Swiss Prot Nº | P29966 |
| Subcellular Location | Cytoplasm, cytoskeleton . Membrane ; Lipid-anchor . |
Other Name: Myristoylated alanine-rich C-kinase substrate (MARCKS) (Protein kinase C substrate, 80 kDa protein, light chain) (80K-L protein) (PKCSL)
Background: The protein encoded by this gene is a substrate for protein kinase C. It is localized to the plasma membrane and is an actin filament crosslinking protein. Phosphorylation by protein kinase C or binding to calcium-calmodulin inhibits its association with actin and with the plasma membrane, leading to its presence in the cytoplasm. The protein is thought to be involved in cell motility, phagocytosis, membrane trafficking and mitogenesis. [provided by RefSeq, Jul 2008],