NAGS rabbit pAb
ENT-A12657
Description
| REF | ENT-A12657 |
|---|---|
| Category | Antibody Polyclonal |
| Description | NAGS rabbit pAb |
| Source | Rabbit |
| Applications | WB;IHC |
| Reactivity | Human; Mouse |
| Reactivity | Human; Mouse |
| Dilution | WB 1:500-2000;IHC-p 1:50-300 |
| Immunogen | Synthesized peptide derived from human NAGS AA range: 361-411 |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | |
| Human Gene ID | 162417 |
| Human Swiss Prot Nº | Q8N159 |
| Subcellular Location | Mitochondrion matrix . |
Other Name:
Background: The N-acetylglutamate synthase gene encodes a mitochondrial enzyme that catalyzes the formation of N-acetylglutamate (NAG) from glutamate and acetyl coenzyme-A. NAG is a cofactor of carbamyl phosphate synthetase I (CPSI), the first enzyme of the urea cycle in mammals. This gene may regulate ureagenesis by altering NAG availability and, thereby, CPSI activity. Deficiencies in N-acetylglutamate synthase have been associated with hyperammonemia. [provided by RefSeq, Jul 2008],