Nuclear Receptor NR4A1 (Phospho-Ser351) Rabbit pAb
ENT-A12576
Description
| REF | ENT-A12576 |
|---|---|
| Category | Antibody Polyclonal |
| Description | Nuclear Receptor NR4A1 (Phospho-Ser351) Rabbit pAb |
| Source | Rabbit |
| Applications | WB; ELISA |
| Reactivity | Human; Mouse; Rat |
| Reactivity | Human; Mouse; Rat |
| Dilution | WB 1:500-2000, ELISA(peptide)1:5000-20000 |
| Immunogen | Synthesized pospho peptide derived from human Nuclear Receptor NR4A1 (Phospho-Ser351) |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | 77kD |
| Human Gene ID | 3164 |
| Human Swiss Prot Nº | P22736 |
| Subcellular Location | Nucleus . Cytoplasm . Mitochondrion . Nuclear export to the cytoplasm is XPO1-mediated and positively regulated by IFI27 (PubMed:22427340). Translocation to the mitochondrion upon interaction with RXRA and upon the presence of 9-cis retinoic acid (PubMed:17761950). . |
Other Name: Nuclear receptor subfamily 4 group A member 1 (Early response protein NAK1;Nuclear hormone receptor NUR/77;Nur77;Orphan nuclear receptor HMR;Orphan nuclear receptor TR3;ST-59;Testicular receptor 3)
Background: This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. Expression is induced by phytohemagglutinin in human lymphocytes and by serum stimulation of arrested fibroblasts. The encoded protein acts as a nuclear transcription factor. Translocation of the protein from the nucleus to mitochondria induces apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2011],