PDE6G Rabbit pAb
ENT-A12430
Description
| REF | ENT-A12430 |
|---|---|
| Category | Antibody Polyclonal |
| Description | PDE6G Rabbit pAb |
| Source | Rabbit |
| Applications | IHC; ELISA |
| Reactivity | Human; Mouse |
| Reactivity | Human; Mouse |
| Dilution | IHC-p 1:50-200, ELISA(peptide)1:5000-20000 |
| Immunogen | Synthesized peptide derived from human PDE6G AA range: 10-90 |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | |
| Human Gene ID | 5148 |
| Human Swiss Prot Nº | P18545 |
| Subcellular Location | plasma membrane,photoreceptor disc membrane, |
Other Name: Retinal rod rhodopsin-sensitive cGMP 3′,5′-cyclic phosphodiesterase subunit gamma (GMP-PDE gamma;EC 3.1.4.35)
Background: This gene encodes the gamma subunit of cyclic GMP-phosphodiesterase, which is composed of alpha- and beta- catalytic subunits and two identical, inhibitory gamma subunits. This gene is expressed in rod photoreceptors and functions in the phototransduction signaling cascade. It is also expressed in a variety of other tissues, and has been shown to regulate the c-Src protein kinase and G-protein-coupled receptor kinase 2. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2009],