PRCC rabbit pAb
ENT-A12312
Description
| REF | ENT-A12312 |
|---|---|
| Category | Antibody Polyclonal |
| Description | PRCC rabbit pAb |
| Source | Rabbit |
| Applications | WB |
| Reactivity | Human;Rat;Mouse; |
| Reactivity | Human;Rat;Mouse; |
| Dilution | WB 1:500-2000 |
| Immunogen | Synthesized peptide derived from human PRCC AA range: 74-124 |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | |
| Human Gene ID | 5546 |
| Human Swiss Prot Nº | Q92733 |
| Subcellular Location | Nucleus . |
Other Name:
Background: This gene encodes a protein that may play a role in pre-mRNA splicing. Chromosomal translocations (X;1)(p11;q21) that result in fusion of this gene to TFE3 (GeneID 7030) have been associated with papillary renal cell carcinoma. A PRCC-TFE3 fusion protein is expressed in affected carcinomas and is likely associated with altered gene transactivation. This fusion protein has also been associated with disruption of the cell cycle.[provided by RefSeq, Aug 2010],
