RAD1 rabbit pAb
ENT-A12229
Description
| REF | ENT-A12229 |
|---|---|
| Category | Antibody Polyclonal |
| Description | RAD1 rabbit pAb |
| Source | Rabbit |
| Applications | IHC;IF;WB |
| Reactivity | Human; Mouse |
| Reactivity | Human; Mouse |
| Dilution | IHC-p 1:50-200, WB 1:500-2000 |
| Immunogen | Synthesized peptide derived from human RAD1 |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | 32kD |
| Human Gene ID | 5810 |
| Human Swiss Prot Nº | O60671 |
| Subcellular Location | Nucleus . |
Other Name: Cell cycle checkpoint protein RAD1 (hRAD1;EC 3.1.11.2;DNA repair exonuclease rad1 homolog;Rad1-like DNA damage checkpoint protein)
Background: This gene encodes a component of a heterotrimeric cell cycle checkpoint complex, known as the 9-1-1 complex, that is activated to stop cell cycle progression in response to DNA damage or incomplete DNA replication. The 9-1-1 complex is recruited by RAD17 to affected sites where it may attract specialized DNA polymerases and other DNA repair effectors. Alternatively spliced transcript variants of this gene have been described. [provided by RefSeq, Jan 2009],