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RSH4A rabbit pAb

RSH4A rabbit pAb

ENT-A12114

Description

 

 

 

REF ENT-A12114
Category Antibody Polyclonal
Description RSH4A rabbit pAb
Source Rabbit
Applications WB
Reactivity Human; Mouse
Reactivity Human; Mouse
Dilution WB 1:500-2000
Immunogen Synthesized peptide derived from human RSH4A AA range: 287-337
Storage Stability -20°C/1 year
Clonality Polyclonal
Isotype IgG
Concentration 1 mg/ml
Observed Band KD
Human Gene ID 345895
Human Swiss Prot Nº Q5TD94
Subcellular Location Cytoplasm, cytoskeleton, cilium axoneme . Cell projection, cilium . Radial spoke. .

Other Name:

Background: This gene encodes a protein that appears to be a component the radial spoke head, as determined by homology to similar proteins in the biflagellate alga Chlamydomonas reinhardtii and other ciliates. Radial spokes, which are regularly spaced along cilia, sperm, and flagella axonemes, consist of a thin ‘stalk’ and a bulbous ‘head’ that form a signal transduction scaffold between the central pair of microtubules and dynein. Mutations in this gene cause primary ciliary dyskinesia 1, a disease arising from dysmotility of motile cilia and sperm. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009],