SSH3 (phospho-Ser37) rabbit pAb
ENT-A11843
Description
| REF | ENT-A11843 |
|---|---|
| Category | Antibody Polyclonal |
| Description | SSH3 (phospho-Ser37) rabbit pAb |
| Source | Rabbit |
| Applications | WB |
| Reactivity | Human;Rat;Mouse; |
| Reactivity | Human;Rat;Mouse; |
| Dilution | WB 1:1000-2000 |
| Immunogen | Synthesized phosho peptide around human SSH3 (Ser37) |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | 74kD |
| Human Gene ID | 54961 |
| Human Swiss Prot Nº | Q8TE77 |
| Subcellular Location | Cytoplasm, cytoskeleton . Nucleus . |
Other Name: Protein phosphatase Slingshot homolog 3 (EC 3.1.3.16) (EC 3.1.3.48) (SSH-like protein 3) (SSH-3L) (hSSH-3L)
Background: The ADF (actin-depolymerizing factor)/cofilin family (see MIM 601442) is composed of stimulus-responsive mediators of actin dynamics. ADF/cofilin proteins are inactivated by kinases such as LIM domain kinase-1 (LIMK1; MIM 601329). The SSH family appears to play a role in actin dynamics by reactivating ADF/cofilin proteins in vivo (Niwa et al., 2002 [PubMed 11832213]).[supplied by OMIM, Mar 2008],