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TIM50 rabbit pAb

TIM50 rabbit pAb

ENT-A11694

Description

 

 

 

REF ENT-A11694
Category Antibody Polyclonal
Description TIM50 rabbit pAb
Source Rabbit
Applications WB
Reactivity Human; Mouse
Reactivity Human; Mouse
Dilution WB 1:500-2000
Immunogen Synthesized peptide derived from human TIM50 AA range: 109-159
Storage Stability -20°C/1 year
Clonality Polyclonal
Isotype IgG
Concentration 1 mg/ml
Observed Band KD 38kD
Human Gene ID 92609
Human Swiss Prot Nº Q3ZCQ8
Subcellular Location Mitochondrion inner membrane ; Single-pass membrane protein .; [Isoform 2]: Nucleus speckle . Nuclear and enriched in speckles with snRNPs. .

Other Name: Mitochondrial import inner membrane translocase subunit TIM50

Background: This gene encodes a subunit of the TIM23 inner mitochondrial membrane translocase complex. The encoded protein functions as the receptor subunit that recognizes the mitochondrial targeting signal, or presequence, on protein cargo that is destined for the mitochondrial inner membrane and matrix. This protein may also play a role in maintaining the membrane permeability barrier, and knockdown of this gene in human cells results in the release of cytochrome c and apoptosis. [provided by RefSeq, Jul 2016],