Tuberin/TSC2 (phospho-Ser1254) rabbit pAb
ENT-A11562
Description
| REF | ENT-A11562 |
|---|---|
| Category | Antibody Polyclonal |
| Description | Tuberin/TSC2 (phospho-Ser1254) rabbit pAb |
| Source | Rabbit |
| Applications | WB |
| Reactivity | Human;Mouse;Rat |
| Reactivity | Human;Mouse;Rat |
| Dilution | WB 1:1000-2000 |
| Immunogen | Synthesized phosho peptide around human Tuberin(Ser1254) |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | 200kD |
| Human Gene ID | 7249 |
| Human Swiss Prot Nº | P49815 |
| Subcellular Location | Cytoplasm. Membrane; Peripheral membrane protein. At steady state found in association with membranes. |
Other Name: Tuberin (Tuberous sclerosis 2 protein)
Background: Mutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008],