ABCA1 rabbit pAb
ENT-A11041
Description
| REF | ENT-A11041 |
|---|---|
| Category | Antibody Polyclonal |
| Description | ABCA1 rabbit pAb |
| Source | Rabbit |
| Applications | WB;ELISA |
| Reactivity | Human;Mouse;Golden hamster |
| Reactivity | Human;Mouse;Golden hamster |
| Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Immunogen | Synthesized peptide derived from part region of human protein AA range: 1112-1180 |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | 248kD |
| Human Gene ID | 19 |
| Human Swiss Prot Nº | O95477 |
| Subcellular Location | Cell membrane ; Multi-pass membrane protein . Endosome . |
Other Name:
Background: The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. With cholesterol as its substrate, this protein functions as a cholesteral efflux pump in the cellular lipid removal pathway. Mutations in this gene have been associated with Tangier’s disease and familial high-density lipoprotein deficiency. [provided by RefSeq, Jul 2008],