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DNMBP rabbit pAb

DNMBP rabbit pAb

ENT-A11019

Description

 

 

 

REF ENT-A11019
Category Antibody Polyclonal
Description DNMBP rabbit pAb
Source Rabbit
Applications WB;ELISA
Reactivity Human;Rat;Mouse;
Reactivity Human;Rat;Mouse;
Dilution WB 1:500-2000 ELISA 1:5000-20000
Immunogen Synthesized peptide derived from part region of human protein AA range: 940-990
Storage Stability -20°C/1 year
Clonality Polyclonal
Isotype IgG
Concentration 1 mg/ml
Observed Band KD 173kD
Human Gene ID 23268
Human Swiss Prot Nº Q6XZF7
Subcellular Location Cytoplasm . Golgi apparatus, Golgi stack . Cytoplasm, cytoskeleton . Cell junction, synapse . Cell junction . Localizes to the apical junction, colocalizes with TJP1. .

Other Name:

Background: This gene encodes a protein belonging to the guanine nucleotide exchange factor family, and which regulates the configuration of cell junctions. It contains multiple binding sites for dynamin and thus links dynamin to actin regulatory proteins. Polymorphisms in this gene have been linked to Alzheimer’s disease in some populations, though there are conflicting reports of such linkages in other populations. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015],