GPVI rabbit pAb
ENT-A10338
Description
| REF | ENT-A10338 |
|---|---|
| Category | Antibody Polyclonal |
| Description | GPVI rabbit pAb |
| Source | Rabbit |
| Applications | WB;ELISA |
| Reactivity | Human;Mouse |
| Reactivity | Human;Mouse |
| Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Immunogen | Synthesized peptide derived from part region of human protein. AA 21-50 |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | 55kD |
| Human Gene ID | 51206 |
| Human Swiss Prot Nº | Q9HCN6 |
| Subcellular Location | [Isoform 1]: Cell membrane; Single-pass membrane protein.; [Isoform 2]: Cell membrane; Single-pass membrane protein. |
Other Name:
Background: This gene encodes a platelet membrane glycoprotein of the immunoglobulin superfamily. The encoded protein is a receptor for collagen and plays a critical role in collagen-induced platelet aggregation and thrombus formation. The encoded protein forms a complex with the Fc receptor gamma-chain that initiates the platelet activation signaling cascade upon collagen binding. Mutations in this gene are a cause of platelet-type bleeding disorder-11 (BDPLT11). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011],