OSTCN rabbit pAb
ENT-A10326
Description
| REF | ENT-A10326 |
|---|---|
| Category | Antibody Polyclonal |
| Description | OSTCN rabbit pAb |
| Source | Rabbit |
| Applications | WB IF;ELISA |
| Reactivity | Human;Rat;Mouse |
| Reactivity | Human;Rat;Mouse |
| Dilution | WB 1:500-2000 IF 1:100-300 ELISA 1:5000-20000 Not yet tested in other applications. |
| Immunogen | Synthesized peptide derived from part region of human protein AA range: 31-80 |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | 11kD |
| Human Gene ID | 632 |
| Human Swiss Prot Nº | P02818 |
| Subcellular Location | Secreted. |
Other Name:
Background: This gene encodes a highly abundant bone protein secreted by osteoblasts that regulates bone remodeling and energy metabolism. The encoded protein contains a Gla (gamma carboxyglutamate) domain, which functions in binding to calcium and hydroxyapatite, the mineral component of bone. Serum osteocalcin levels may be negatively correlated with metabolic syndrome. Read-through transcription exists between this gene and the neighboring upstream gene, PMF1 (polyamine-modulated factor 1), but the encoded protein only shows sequence identity with the upstream gene product. [provided by RefSeq, Jun 2015],