TNR8 rabbit pAb
ENT-A10130
Description
| REF | ENT-A10130 |
|---|---|
| Category | Antibody Polyclonal |
| Description | TNR8 rabbit pAb |
| Source | Rabbit |
| Applications | WB;IHC;IF;ELISA |
| Reactivity | Human;Rat;Mouse |
| Reactivity | Human;Rat;Mouse |
| Dilution | WB 1:500-2000 IHC-p: 50-200 ELISA 1:5000-20000 |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | 65kD |
| Human Gene ID | 943 |
| Human Swiss Prot Nº | P28908 |
| Subcellular Location | [Isoform 1]: Cell membrane ; Single-pass type I membrane protein .; [Isoform 2]: Cytoplasm . |
Other Name:
Background: The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008],