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UBP10 rabbit pAb

UBP10 rabbit pAb

ENT-A9700

Description

 

 

 

REF ENT-A9700
Category Antibody Polyclonal
Description UBP10 rabbit pAb
Source Rabbit
Applications WB;ELISA
Reactivity Human;Rat;Mouse
Reactivity Human;Rat;Mouse
Dilution WB 1:500-2000 ELISA 1:5000-20000
Immunogen Synthesized peptide derived from part region of human protein
Storage Stability -20°C/1 year
Clonality Polyclonal
Isotype IgG
Concentration 1 mg/ml
Observed Band KD 87kD
Human Gene ID 9100
Human Swiss Prot Nº Q14694
Subcellular Location Cytoplasm . Nucleus . Early endosome . Cytoplasmic in normal conditions (PubMed:20096447). After DNA damage, translocates to the nucleus following phosphorylation by ATM (PubMed:20096447). .

Other Name:

Background: Ubiquitin is a highly conserved protein that is covalently linked to other proteins to regulate their function and degradation. This gene encodes a member of the ubiquitin-specific protease family of cysteine proteases. The enzyme specifically cleaves ubiquitin from ubiquitin-conjugated protein substrates. The protein is found in the nucleus and cytoplasm. It functions as a co-factor of the DNA-bound androgen receptor complex, and is inhibited by a protein in the Ras-GTPase pathway. The human genome contains several pseudogenes similar to this gene. Several transcript variants, some protein-coding and others not protein-coding, have been found for this gene. [provided by RefSeq, Jan 2013],