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SYT5 rabbit pAb

SYT5 rabbit pAb

ENT-A9626

Description

 

 

 

REF ENT-A9626
Category Antibody Polyclonal
Description SYT5 rabbit pAb
Source Rabbit
Applications WB;ELISA
Reactivity Human;Rat;Mouse
Reactivity Human;Rat;Mouse
Dilution WB 1:500-2000 ELISA 1:5000-20000
Immunogen Synthesized peptide derived from part region of human protein
Storage Stability -20°C/1 year
Clonality Polyclonal
Isotype IgG
Concentration 1 mg/ml
Observed Band KD 42kD
Human Gene ID 6861
Human Swiss Prot Nº O00445
Subcellular Location Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane ; Single-pass membrane protein . Recycling endosome membrane ; Single-pass membrane protein . In mast cells, localizes to the endocytic recycling compartment. .

Other Name:

Background: Synaptotagmins, such as SYT5, are a family of type III membrane proteins characterized by cytoplasmic repeats related to protein kinase C (see MIM 176960) regulatory (C2) domains, which are thought to bind calcium. Synaptotagmins may act both as negative regulators of vesicle fusion, allowing fusion in the presence of calcium, and as calcium receptors or sensor molecules (summary by Hudson and Birnbaum, 1995 [PubMed 7597049]).[supplied by OMIM, Feb 2011],