PR40A rabbit pAb
ENT-A9337
Description
| REF | ENT-A9337 |
|---|---|
| Category | Antibody Polyclonal |
| Description | PR40A rabbit pAb |
| Source | Rabbit |
| Applications | WB;ELISA |
| Reactivity | Human;Mouse |
| Reactivity | Human;Mouse |
| Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Immunogen | Synthesized peptide derived from human protein . at AA range: 450-530 |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | 105kD |
| Human Gene ID | 55660 |
| Human Swiss Prot Nº | O75400 |
| Subcellular Location | Nucleus speckle . Nucleus matrix . Colocalizes with AKAP8L in the nuclear matrix. . |
Other Name:
Background: domain:The WW domains are essential for localization to nuclear speckles.,function:Binds to WASL/N-WASP and suppresses its translocation from the nucleus to the cytoplasm, thereby inhibiting its cytoplasmic function (By similarity). May be involved in pre-mRNA splicing.,sequence caution:Contaminating sequence. Potential poly-A sequence starting in position 409.,sequence caution:Contaminating sequence. Potential poly-A sequence.,similarity:Belongs to the PRPF40 family.,similarity:Contains 2 WW domains.,similarity:Contains 5 FF domains.,subunit:Interacts with the N-terminus of HTT. Interacts with the phosphorylated carboxyterminal domain of POLR2A. Interacts with SF1, SRPK1 CARD8, ATBF1 and MECP2 (By similarity). Interacts through the WW domains with formin proline-rich regions and with WASL/N-WASP.,tissue specificity:Widely expressed.,