MAP4 rabbit pAb
ENT-A8234
Description
| REF | ENT-A8234 |
|---|---|
| Category | Antibody Polyclonal |
| Description | MAP4 rabbit pAb |
| Source | Rabbit |
| Applications | WB;ELISA |
| Reactivity | Human;Mouse;Rat |
| Reactivity | Human;Mouse;Rat |
| Dilution | WB 1:500-2000, ELISA 1:10000-20000 |
| Immunogen | Synthesized peptide derived from human MAP4 Polyclonal |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | 85kD |
| Human Gene ID | 4134 |
| Human Swiss Prot Nº | P27816 |
| Subcellular Location | Cytoplasm, cytoskeleton . Cytoplasm, cytoskeleton, microtubule organizing center . Recruitment to microtubule is inhibited by microtubules polyglutamylation. . |
Other Name: Microtubule-associated protein 4 (MAP-4)
Background: The protein encoded by this gene is a major non-neuronal microtubule-associated protein. This protein contains a domain similar to the microtubule-binding domains of neuronal microtubule-associated protein (MAP2) and microtubule-associated protein tau (MAPT/TAU). This protein promotes microtubule assembly, and has been shown to counteract destabilization of interphase microtubule catastrophe promotion. Cyclin B was found to interact with this protein, which targets cell division cycle 2 (CDC2) kinase to microtubules. The phosphorylation of this protein affects microtubule properties and cell cycle progression. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008],