AVP Receptor V3 rabbit pAb
ENT-A8121
Description
| REF | ENT-A8121 |
|---|---|
| Category | Antibody Polyclonal |
| Description | AVP Receptor V3 rabbit pAb |
| Source | Rabbit |
| Applications | IHC;IF;ELISA |
| Reactivity | Human;Mouse;Rat |
| Reactivity | Human;Mouse;Rat |
| Dilution | IHC-p 1:50-200, ELISA 1:10000-20000 |
| Immunogen | The antiserum was produced against synthesized peptide derived from the Internal region of human AVPR1B. AA range:271-320 |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | |
| Human Gene ID | 553 |
| Human Swiss Prot Nº | P47901 |
| Subcellular Location | Cell membrane ; Multi-pass membrane protein . |
Other Name: Vasopressin V1b receptor (V1bR;AVPR V1b;AVPR V3;Antidiuretic hormone receptor 1b;Vasopressin V3 receptor)
Background: The protein encoded by this gene acts as receptor for arginine vasopressin. This receptor belongs to the subfamily of G-protein coupled receptors which includes AVPR1A, V2R and OXT receptors. Its activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system. The receptor is primarily located in the anterior pituitary, where it stimulates ACTH release. It is expressed at high levels in ACTH-secreting pituitary adenomas as well as in bronchial carcinoids responsible for the ectopic ACTH syndrome. A spliced antisense transcript of this gene has been reported but its function is not known. [provided by RefSeq, Jul 2008],