Chordin rabbit pAb
ENT-A8116
Description
| REF | ENT-A8116 |
|---|---|
| Category | Antibody Polyclonal |
| Description | Chordin rabbit pAb |
| Source | Rabbit |
| Applications | IHC;IF;ELISA |
| Reactivity | Human;Mouse;Rat |
| Reactivity | Human;Mouse;Rat |
| Dilution | IHC-p 1:50-200, ELISA 1:10000-20000 |
| Immunogen | The antiserum was produced against synthesized peptide derived from the C-terminal region of human CHRD. AA range:905-954 |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | |
| Human Gene ID | 8646 |
| Human Swiss Prot Nº | Q9H2X0 |
| Subcellular Location | Secreted . |
Other Name: Chordin
Background: This gene encodes a secreted protein that dorsalizes early vertebrate embryonic tissues by binding to ventralizing TGF-beta-like bone morphogenetic proteins and sequestering them in latent complexes. The encoded protein may also have roles in organogenesis and during adulthood. It has been suggested that this gene could be a candidate gene for Cornelia de Lange syndrome. Reduced expression of this gene results in enhanced bone regeneration. Alternative splicing results in multiple transcript variants. Other alternative splice variants have been described but their full length sequence has not been determined. [provided by RefSeq, Jan 2015],