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Integrin αX rabbit pAb

Integrin αX rabbit pAb

ENT-A8046

Description

 

 

 

REF ENT-A8046
Category Antibody Polyclonal
Description Integrin αX rabbit pAb
Source Rabbit
Applications IHC;IF;ELISA
Reactivity Human;Rat;Mouse;
Reactivity Human;Rat;Mouse;
Dilution IHC-p 1:50-200, ELISA 1:10000-20000
Immunogen Synthetic peptide from human protein at AA range: 920-980
Storage Stability -20°C/1 year
Clonality Polyclonal
Isotype IgG
Concentration 1 mg/ml
Observed Band KD
Human Gene ID 3687
Human Swiss Prot Nº P20702
Subcellular Location Membrane; Single-pass type I membrane protein.

Other Name: Integrin alpha-X (CD11 antigen-like family member C;Leu M5;Leukocyte adhesion glycoprotein p150,95 alpha chain;Leukocyte adhesion receptor p150,95;CD antigen CD11c)

Background: integrin subunit alpha X(ITGAX) Homo sapiens This gene encodes the integrin alpha X chain protein. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4). The alpha X beta 2 complex seems to overlap the properties of the alpha M beta 2 integrin in the adherence of neutrophils and monocytes to stimulated endothelium cells, and in the phagocytosis of complement coated particles. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013],